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EC number: 246-613-9 | CAS number: 25103-09-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March 05, 2010 to May 10, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Batch No. 04.12.09.H
Purity: 99.87% - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): domestic wastewater treatment plant (sewage works, Darmstadt, Germany).
- Preparation of inoculum for exposure: centrifugation, resuspension of solid mterial in tap water (repeat three (3) time).
- Pretreatment: Aliqout of wet sludge material was weighed, dried, and the ratio of wet sludge material to dry weight was determined.
- Concentration of sludge: Aliqouts corresponding to 1.5 g dry sludge material were mixed with one (1) liter of test water (equals 1.5 g/L). - Duration of test (contact time):
- 28 d
- Initial conc.:
- 102 mg/L
- Based on:
- ThOD
- Remarks:
- Oxygen demand of about 249 mg/L
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- Calculated from the decrease of pressure in the reaction vessel.
- Details on study design:
- Principle: The test flasks were incubated at 22 ± 2 °C. The pressure decrease in the reaction vessels was measured over complete experimental phase of 28 days using the BSB Sensomat system. The test flasks were closed gas-tight by a measuring head. Potassium hydroxide solution (45%) was used for trapping the produced carbon dioxide. The amount of O2 consumed by the activated sludge was calculated from the decrease of pressure in the reaction vessel.
Identification: Each test unit was uniquely identified with the study number, treatment and replicate number. - Reference substance:
- benzoic acid, sodium salt
- Test performance:
- Inoculum Control: The oxygen demand of the inoculum control (medium and inoculum) was 20 mg O2/L and thus not greater than 60 mg
O2/L within 28 days as required by the test guideline.
pH-Value:The pH-value of the test item flasks at the end of the test was within the range of pH 6.0 to 8.5 as required by the test guideline.
Reference Item: The percentage degradation of the reference item should reach the level for ready biodegradability (>60%) within 14 days as required by the test guideline.
The reference item sodium benzoate was degraded to more than 60% after 4 days of incubation.
Test Item: The difference of duplicate values for the degradation of the test item at the plateau, at the end of the test and at the end of the 10-day window should be less than 20%. The validity criterion was fulfilled. - Key result
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- Flask 1 and 2
- Value:
- 76
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable, but failing 10-day window
- Conclusions:
- The degradation rate of iOTG reached 76% after 28 days of incubation. According to the test guideline, iOTG is considered to be readily biodegradable.
- Executive summary:
-
The degradation rate of iOTG reached 76% after 28 days of incubation; the 10-day window criterion was curtly not passed. According to the test guideline, iOTG is considered to be readily biodegradable.
Reference
Description of key information
The readily biodegradation potential of isooctyl thioglycolate (iOTG) has been investigated through the OECD 301F methodology. The results concluded that iOTG is ready biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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