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EC number: 227-615-9 | CAS number: 5908-81-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05 November 2014 - 07 June 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-compliant study in accordance with EC A.8, OECD 107 and EPA OPPTS 830.7550.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- (2008)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Version / remarks:
- (1995)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
- Version / remarks:
- (1996)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Barium tartrate
- EC Number:
- 227-615-9
- EC Name:
- Barium tartrate
- Cas Number:
- 5908-81-6
- Molecular formula:
- C4H4O6Ba
- IUPAC Name:
- Barium L(+)-(2R,3R)-tartrate
- Details on test material:
- - Name of test material (as cited in study report): Barium tartrate
- Appearance: White powder
Constituent 1
Study design
- Analytical method:
- other: ICP-MS (see IUCLID Section 8)
Results and discussion
Partition coefficientopen allclose all
- Type:
- Pow
- Partition coefficient:
- < 0
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: Mean value (n=6). Standard deviation: 0.00041
- Type:
- log Pow
- Partition coefficient:
- < -3.4
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: Mean value (n=6)
- Details on results:
- - Preliminary test: the content of test substance dissolved in the n-octanol sample was 0.0017 mg/L
Main study:
- The log Pow values fell within the criterion range of ± 0.3 log units (see table below)
- The mean analysed concentration of the substance in the stock solution was 0.0346 g/L. Based on this, the nominal quantity of the test substance in each test vessel was 0.0692 mg. The recoveries were determined according to this value.
- The quantity analysed in each of the test vessels was in the range of 0.0679 - 0.0718 mg; the recoveries were thus between 98 and 104%.
Any other information on results incl. tables
Shake-flask method results
Ratio |
Analysed concentration |
Pow |
log Pow |
pH |
||
n-octanol |
water |
individual |
mean |
|||
|
|
|
|
|
|
|
1:1 |
<2.11E-06 |
0.0120 |
<1.8 x 10-4 |
<1.8 x 10-4 |
< -3.8 |
7.0 |
|
<2.09E-06 |
0.0116 |
<1.8 x 10-4 |
|
< -3.8 |
7.0 |
|
|
|
|
|
|
|
1:2 |
8.84E-06 |
0.00898 |
9.8 x 10-4 |
<6.1 x 10-4 |
< -3.0 |
7.0 |
|
<2.09E-06 |
0.00881 |
<2.4 x 10-4 |
|
< -3.6 |
7.0 |
|
|
|
|
|
|
|
2:1 |
1.60E-05 |
0.0169 |
9.5 x 10-4 |
<5.3 x 10-4 |
< -3.0 |
7.0 |
|
<2.13E-06 |
0.0175 |
<1.2 x 10-4 |
|
< -3.9 |
7.0 |
|
|
|
|
|
|
|
No test substance was detected in the pre-treated samples from the blank mixture. Therefore no correction was applied on the results.
Applicant's summary and conclusion
- Conclusions:
- In a GLP-compliant study in accordance with EC A.8, OECD 107 and EPA OPPTS 830.7550 using the shake-flask method, the log Pow of the substance at pH 7 and 20°C was determined as < -3.4 (Pow: < 0.00044).
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