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EC number: 208-594-5 | CAS number: 534-22-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
In order to determine the classification for hazardous properties related to the aquatic environment, the criteria of the Regulation (EC) No 1272/2008 (CLP) version 2016 in Annex I were accurately followed.
Short-term (acute) aquatic hazard:
For classification, acute toxicity data are available for fish and aquatic invertebrates (Daphnia):
Fish: average LC50 (48h) = 431.5 mg/L (average of 237 and 626 mg/L)
Daphnia: EC50 (24h) = 888 mg/L
The criteria in Table 4.1.0 (a) of Annex I of the CLP Regulation were applied.
The lowest EC50 value was observed for fish, which is hence the most sensitive species. It is important to note that the aquatic toxicity studies were not performed according to the OECD guideline, and that the exposure duration deviates from the standard exposure period. For fish, exposure was 48h instead of the prescribed 96h, and for Daphnia exposure was 24h instead of 48h. Nevertheless, given that the EC50 values are many times higher than the cut-off for classification being 1 mg/L, it is safe to state that according to Table 4.1.0 (a) the substance should not be classified for acute aquatic hazard, as the lowest EC50 value is 237 mg/L, which is well above the cut-off for classification of 1 mg/L.
Long-term (chronic) aquatic hazard:
For chronic classification, there are only chronic data available for one trophic level, algae. As described in Figure 4.1.1 in the CLP regulation (EC No 1272/2008, version 2016), the most stringent outcome of classification according to Table 4.1.0 (b) (i) or (ii) and (iii) should be used.
Table 4.1.0 (b) (i):
The substance is assumed to be not readily biodegradable, hence Table 4.1.0 (b) (i) applies.
The NOEC (8d) was 40 mg/L. Since the NOEC is well above the classification cut-off of 1 mg/L, the substance should not be classified.
Also here it is important to note that the duration of the algae test was 8d which is not in line with the OECD 201 guideline which prescribes 72 or 96h exposure. Nevertheless, it is safe to state that the substance should not be classified given that the NOEC value is 40 times larger than the classification cut-off.
Table 4.1.0 (b) (iii):
Classification based on available acute data available for the other trophic levels and environmental fate data:
Fish: average LC50 (48h) = 431.5 mg/L (average of 237 and 626 mg/L)
Daphnia: EC50 (24h) = 888 mg/L
Log Kow = 1.85
The substance is not readily biodegradable.
Based on the criteria Table 4.1.0 (b) (iii), the substance should not be classified as chronic aquatic toxic, since the lowest EC50 value for fish is > 100 mg/L and the substance is not readily biodegradable.
Most stringent chronic classification:
The conclusion of both assessment is that the substance should not be classified for chronic aquatic hazard.
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