Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-813-0 | CAS number: 110-89-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The substance is with high probability acutely not harmful to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Remarks:
- Leuciscus idus; test performed with pH-adjustment
- Effect concentration:
- > 100 mg/L
Additional information
The key study, a test according to DIN 38 412 ("Bestimmung der Wirkung von Wasserinhaltsstoffen auf Fische - Fischtest (L15)"), was performed with Leuciscus idus over 96h by BASF AG (1987, report no. 10F0180/875094). The non-GLP study was consistent with all validity criteria of the guideline. Test concentrations were not analytically verified in the static toxicity test. However, from an available acute toxicity study on aquatic invertebrates, conducted with analytical monitoring and recovery rates from 91 to 108 % (BASF SE, 2013, 50E0108/09X103), it can be concluded that piperidine is rather stable in static test systems for at least 48 hours. Moreover, the stability of piperidine in the test medium is considered to be stable over the exposure period based on a sufficient water solubility, a low Henry's Law constant of 1.74 Pa m³/mol (HENRYWIN v3.20, EPI Suite v 4.11) and a low adsorption potential (log Kow = 1.18, EPIWin calculation, BASF SE, 2011; log Koc = 2.3 at pH 5 to 8, calculated according to Franco&Trapp, BASF SE, 2021).
The 96 -h LC50 was determined to be 68.12 mg/L (geometric mean, nominal, not pH-adjusted). All fish died in the highest test concentration of 100 mg/L without pH-adjustment, while there was no mortality observed after the pH-adjustment of the highest test concentration (100 mg/L).
The result is supported by a fish embryo test similar to OECD 236 with Danio rerio. The 48-h LC50 was determined to be 110 mg/L (nominal, not pH-adjusted; Brust, 2001).
In conclusion, the test substance is considered to be acutely not harmful to fish after pH-adjustment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.