Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 203-181-6 | CAS number: 104-16-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
If inhaled: remove the victim to fresh air and keep at rest in a position confortable for breathing. If breathing difficulties persist due to accidental inhalation of dust, vapours, aerosols or combustion fumes, provide oxygen and/or artificial respiration. Seek medical assistance.
If in eyes: rinse cautiously and thoroughly with plenty of water. Remove contact lenses, if present and easy to do; continue rinsing. If eyes irritation persists, get medical assistance.
If on skin and clothes: remove contaminated clothing and shoes. Wash thoroughly with soap and water. Wash clothing before re-use.
If ingested: Contact immediately a POISON CENTER or a doctor. Rinse repeatedly the mouth with water without swallowing. Do not induce vomiting or administer anything without medical advice.
Fire-fighting measures
Extinguishing media: foam, water spray, carbon dioxide, chemical powder. Do not use water in proximity of electrical apparatus.
Danger in case of fire: possible evolution of toxic/corrosive fumes of carbon monoxide, carbon dioxide, nitrogen oxide, hydrochloric acid.
Protective device for fire-fighting people: protetcive device/clothing for head, hands, skin and eyes. Self-contained breathing apparatus.
Fire-fighting water/media and fire residues must be disposed as hazardous wastes. in compliance with current Regulations.
Accidental release measures
Environmental: prevent dispersed material to reach sewers and water courses.
Methods for cleaning up: use inert absorbents (sand, kieselgur,,,); collect mechanically the released material and dispose according to waste handling procedures, Ventilate the area, if proper; if necessary wash with water disposing the resulting liquid as hazardous waste.
Handling and storage
Emissions: captured air and process emissions should be properly handled before immission in atmosphere (gaseous emissions purification system).
Waste: waste deriving from activities involving the substance should be considered hazardous and handled as such.
Storage Store in well closed, leakproof containers in well ventilated, dedicated area. Prevent/protect from contact with electrostatic charges or other ignition sources. Avoid moisture, light exposition and proximity with incompatible materials (strong acid and bases, oxidants).
Further measures: as additional, redundant protection measures, workers should wear proper PPE for skin (overalls), hands (gloves), eyes (googles) and breathing apparatus (mask) when handling the substance. Strictly follow directions for use, cleaning and maintenance reported by the supplier for each kind of PPE. Wash accurately before re-use.
Transport information
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Marine transport (UN RTDG/IMDG)
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Exposure controls / personal protection
A periodical check of workers exposition to the substance is carried out. Qualified personnel evaluates the results in order to implement further prevention/protection measures, if proper.
Stability and reactivity
Conditions to avoid: very high temperatures could origin decomposition with emission of toxic/irritating/corrosive fumes.
Thermal decomposition could result in emission of oxides of Carbon and Nitrogen and of Hydrochloric acid.
Materials to avoid: strong acid and bases; oxidizing agents. Light exposure causes darkening of the substance.
Disposal considerations
Disposal of waste: keep in well closed containers and send waste (including contaminated containers) to authorized companies for disposal,
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.