Registration Dossier
Registration Dossier
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EC number: 229-542-8 | CAS number: 6600-31-3
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In all in-vitro genetic toxicity assays (Ames test, MNT, V79/HGPRT test), 3,9-Di-3-cyclohexen-1-yl-2,4,8,10-tetraspiro[5.5]undecane
was negative.Justification for selection of genetic toxicity endpoint
The results of the Ames tests, the in-vitro MNT test and the HPRT test were considered
Short description of key information:
3,9 -Di-3 -cyclohexen-1 -yl-2,4,8,10 -tetraspiro[5.5]undecane, CAS 6600-31-3 was investigated in 2 Salmonella/microsome tests (Ames tests). Result: negative, no evidence of mutagenic activity was seen (with and without mutagenic activation). Additional, 3,9 -Di-3 -cyclohexen-1 -yl-2,4,8,10 -tetraspiro[5.5]undecane was evaluated as negative in an in-vitro MNT and also in a V79/HGPRT test.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Due to the negative reaults in all available in-vitro genetic toxicity tests a classification is not justified.
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