Registration Dossier

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

water solubility
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP status not known, guideline not known, information from published handbook, data compendium, review article or other reference text, acceptable with restrictions
not specified
Principles of method if other than guideline:
The use of secondary sources of data is acceptable when they are based on a critical evaluation of peer-reviewed data and a consequent selection of a reliable and representative value for the property under investigation. The introduction to the Handbook of Aqueous Solubility Data states that it is an extensive compilation of published data. Each record is evaluated against a five point scheme based on the reporting of temperature, purity of the solute, equilibration time/agitiation, analysis and accuracy and/or precision, allowing the reader to select the most reliable and representative value. Therefore, although the method used is not known, the values presented here are acceptable as they are from a reliable secondary source of phys chem. data.
GLP compliance:
not specified
Type of method:
other: Not known
Key result
Water solubility:
48.2 mg/L
25 °C
Remarks on result:
other: pH not reported
Details on results:
Temperature: given with range. Purity of solute: stated with range or altered with range or calculated. Equilibrium time/agitation: described in detail. Analysis: described in detail. Accuracy and/or precision: 3 significant figures or range 0-5%. The solubility reported is the preferred value quoted in the source. pH not reported.

pH not reported.

Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of mesitylene (1,3,5-trimethylbenzene) at 25 °C was measured to be 48.2 mg/L.
Executive summary:

No information on the methods used is available. However, this information is taken from a reliable peer reviewed handbook and is considered reliable and suitable for use as the key study for this endpoint. The water solubility of mesitylene (1,3,5-trimethylbenzene) at 25 °C was measured to be 48.2 mg/L.

Description of key information

The water solubility of mesitylene (1,3,5-trimethylbenzene) at 25 °C was determined to be 48.2 mg/L.

Key value for chemical safety assessment

Water solubility:
48.2 mg/L
at the temperature of:
25 °C

Additional information

The handbook by Yalkowsky (2003) is peer-reviewed and is considered reliable and suitable for use as a key study for this endpoint. The supporting study (Sanemasa et al 1982) is an experimental study, published in peer reviewed literature and reports a value of 49.8 mg/L.