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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999
Report Date:
1999

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EPA OPPTS 870.1300 (Acute inhalation toxicity)
Deviations:
no
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 403 (Acute Inhalation Toxicity)
Deviations:
no
Test type:
standard acute method
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: aerosol
Type of inhalation exposure:
nose only

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
LC50
Effect level:
3.97 mg/L air (analytical)
95% CL:
>= 2.25 - <= 5.69
Exp. duration:
4 h
Sex:
female
Dose descriptor:
LC50
Effect level:
7.42 mg/L air (analytical)
95% CL:
>= -4.75 - <= 19.6
Exp. duration:
4 h
Sex:
male/female
Dose descriptor:
LC50
Effect level:
5.08 mg/L air (analytical)
95% CL:
>= 1.9 - <= 8.27
Exp. duration:
4 h
Sex:
male
Dose descriptor:
LC50
Effect level:
2.79 other:
95% CL:
>= 1.73 - <= 3.85
Exp. duration:
4 h
Sex:
female
Dose descriptor:
LC50
Effect level:
5.03 other:
95% CL:
>= -2.47 - <= 12.53
Exp. duration:
4 h
Sex:
male/female
Dose descriptor:
LC50
Effect level:
3.56 other:
95% CL:
>= 1.47 - <= 5.64
Exp. duration:
4 h

Applicant's summary and conclusion