Registration Dossier
Registration Dossier
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EC number: 439-070-6 | CAS number: 125005-87-0
Endpoint summary
Administrative data
Description of key information
Reliable studies of acute oral and acute inhalation toxicity in the rat are available. Both found no deaths and no significant toxicity.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Value:
- mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Value:
- mg/m³ air
Additional information
The rat acute oral toxicity study found no evidence of toxicity following administration of test substance at 5000 mg/kg. In the inhalation study, rats exposed for 4 hours to a dust atmosphere nominally 4.9 mg.l (measured concentration 0.316 mg/l) showed a similar absence of adverse reaction (including an absence of treatment-related histopathological change in the lungs and tracheae). The difference between nominal and measured concentrations in this study may indicate that close to a maximum practicable concentration was achieved, and it is also notable that particle size analysis of the test substance in its commercial form found 50.9% to have particle size =/> 45 microns.
Justification for classification or non-classification
The results of acute toxicity indicate that no classification for this endpoint is appropriate.
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