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Diss Factsheets
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EC number: 442-680-5 | CAS number: 443688-20-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 12th to September 11th, 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.2 (Acute Toxicity for Daphnia)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Red LF 6339
- IUPAC Name:
- Red LF 6339
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- samples were takedn just before test start (duplicate samples from the single test medium and duplicate samples from the control without daphnids)
after 48 hours - stability samples (duplicate samples from the single test medium and duplicate samples from the control
Test solutions
- Details on test solutions:
- test solution prepared by dissolving 30 mg test item completely in 300 ml test water by intense stirring for 10 minutes at RT
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Strain/clone: clone 5
- Source: originally supplied by the University of Sheffield/UK
- Age at the start of the test (mean and range, SD): 6-24 hrs old and are not first brood progeny
- Feeding during test: none
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 2.5 mmol/l as CaCO
- Test temperature:
- 20-21 °C
- pH:
- 7.9-8.0
- Dissolved oxygen:
- >8.0 mg/l
- Nominal and measured concentrations:
- 100 mg/l (nominal)
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 100-ml glass beaked filled with 50 ml test medium
- Type (delete if not applicable): covered with glass plates
- Aeration: test water aerated prior to the start of the study until oxygen saturation was reached. During the test period the test water was not aerated
- No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): two
- No. of vessels per control (replicates): two
- Biomass loading rate: < one daphina per 2 ml test medium
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted test water
- Alkalinity: 0.8 mmol/l
- Ca/mg ratio: 4/1
- Culture medium different from test medium: no
- Intervals of water quality measurement: at the start and at the end of the test, pH values, the dissolved oxygen concentrations and the water temperature were determined in the single test concentration and the control. The appearance of the test medium was visually recorded at the start of the test and after 24 and 48 hours.
OTHER TEST CONDITIONS
- Photoperiod: 16-hr light and 8 hr darkness with 30 minute transition period
- Light intensity: 550-685 lux
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : daphnids were observed form immobility after 24 and 48 hrs of exposure - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- the test item is suffuciently stable in the test water under test conditions.
analytically determined mean test item concentration in the test medium varied from 100-98 % of the nominal value.
mean measured test item concentration corresponded to 99 % of the nominal value
No remarkable observations were made concerning the appearance of the test medium
the test item has no toxic effect on Daphnia magna
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- NOEC(48h) = 100 mg/l
EC0(48h) = 100 mg/l
EC50(48h) >100 mg/l
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