Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 478-130-6 | CAS number: 50940-49-3
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
The kinetics of the study have been determined to be consistent with that of a pseudo-first order reaction as the graphs of Iog10 concentration versus time are straight lines.
It has been observed that the rate of hydrolysis increases with an increase in pH.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 156 d
- at the temperature of:
- 25 °C
Additional information
The determination was carried out using Method C7 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The kinetics of the study have been determined to be consistent with that of a pseudo-first order reaction as the graphs of log10 concentration versus time are straight lines. It has been observed that the rate of hydrolysis increases with an increase in pH. The hydrolysis pathway was anticipated to be base catalysed hydrolysis/cleavage of the test material at either of the two ester bonds. Therefore possible primary hydrolysis products may be, but not limited to:
• Butanedioic acid
• 2 -Propenoic acid, 2 -hydroxyethyl ester
• 2-Propenoic acid
• Butanedioic acid, mono 2-hydroxyethyl ester
The rate constant and estimated half-life at 25°C of the test material are shown in the following table:
pH |
Rate Constant (s-1) |
Estimated Half-life at 25oC |
4 |
2.72 x 10-8 |
295 days |
7 |
5.13 x 10-8 |
156 days |
9 |
4.14 x 10-6 |
46.5 hours |
The estimated half-life at 25 oC 295 days (pH = 4), 156 days (pH = 7) and 46.5 hours (pH = 9) indicates that significant exposure to the parent compound in the environment over a long period of time is not of significant concern.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
