Registration Dossier
Registration Dossier
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EC number: 202-805-4 | CAS number: 99-97-8
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: long-term
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- terrestrial toxicity (Earthworm) by ECOSAR Version 1.10
- Author:
- ECOSAR Version 1.10
- Year:
- 2 012
- Bibliographic source:
- ECOSAR v1.1 Class-specific Estimations, Environmental Protection Agency (EPA) office of Chemical Safety and Pollution Prevention
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- ECOSAR Program (v1.00)
- GLP compliance:
- no
Test material
- Reference substance name:
- N,N-dimethyl-p-toluidine
- EC Number:
- 202-805-4
- EC Name:
- N,N-dimethyl-p-toluidine
- Cas Number:
- 99-97-8
- Molecular formula:
- C9H13N
- IUPAC Name:
- N,N,4-trimethylaniline
- Details on test material:
- - Name of test material: N,N-dimethyl-p-toluidine
- Molecular formula: C9H13N
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test substrate
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- other: Earthworm
- Animal group:
- annelids
Study design
- Study type:
- other: no data
- Substrate type:
- not specified
- Limit test:
- yes
- Total exposure duration:
- 14 d
Test conditions
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 14 d
- Dose descriptor:
- LC50
- Effect conc.:
- 198.045 other: mg/L (ppm)
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 14 day toxicity (LC50) to earthworm by N,N-dimethyl-p-toluidine as estimated by the ECOSAR model was 198.045 mg/L.
- Executive summary:
The 14 day toxicity (LC50) to earthworm by N,N-dimethyl-p-toluidine as estimated by the ECOSAR model was 198.045 mg/L.
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