Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 406-040-9 | CAS number: 125643-61-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations. No toxic effects occur at the range of solubility.
Key value for chemical safety assessment
Additional information
Assessment of the parent compound Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-,C7-9-branched alkyl esters (CAS: 125643 -61 -0)
Short term respiration test (OECD 209):
In a short term respiration test according to OECD guideline 209, no respiration inhibition of domestic activated sludge was observed over a period of 3 hours at 100 mg/L test substance concentration (CIBA-GEIGY 1989). Therefore, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Supporting assessment of the impurity Metilox (CAS 6386-38-5)
In a 3 h acute toxicity study to sewage sludge microorganisms the IC50 value based on respiration rate was bigger than 100 mg/L after a 3 h contact time.
Supporting assessment of the major degradation product Metilox acid (CAS: 20170-32-5)
In a 3 hours activated sludge respiration inhibition test the IC50 concentration of the test substance was found to be greater than 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
