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Long-term toxicity to aquatic invertebrates

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Description of key information

Hydrocarbons, C10-C12, isoalknes, <2% aromatics, showed no effects on survival, reproduction, or length at nominal and measured concentrations of 0.026 and 0.025 mg/L, respectively. Therefore, the 21-Day No Observed Effect Loading Rate (NOELR) and No Observed Effect Concentration (NOEC) values are 0.026 and 0.025 mg/L, respectively, for these endpoints based upon nominal loading rates and measured (geometric means) concentrations. In a second 21-day study, the adult daphnids exposed to hydrocarbons, C10-C12, isoalkanes, <2% aromatics, at a loading rate of 1 mg/L produced significantly fewer (<0.05) live offspring per adult than the adult daphnids in the control media. Therefore, the 21-day NOELR for reproduction was reported as <1 mg/L. There was 10% immobility of parents in the treatment solution, which was equivalent to the control mortality, therefore the EL50 can be reported as >1 mg/L. In a third 21-day study, the hydrocarbons, C13 -C16, isoalkanes, cyclics, <2% aromatics, Daphnia magna, 21 -day EL50 value based on adult immobilization and reduction in reproduction was >5 mg/L. The hydrocarbons, C13 -C16, isoalkaes, cyclics, <2% aromatics, Daphnia magna, 21 -day No Observed Effect Loading Rate (NOELR) based on adult immobilization and reduction in reproduction was 5 mg/L. The data from these three studies are used as read-across data to Raffinates (Fischer-Tropsch), C10-C25-branched hydrocarbon fluids.
During the 21-day study, the adult daphnids exposed to the test substance at a loading rate of 1 mg/L produced significantly fewer (<0.05) live offspring per adult than the adult daphnids in the control media. Therefore, the 21-day NOELR for reproduction was <1 mg/L. There was 10% immobility of parents in the treatment solution, which was equivalent to the control mortality, therefore the EL50 can be reported as >1 mg/L.

Key value for chemical safety assessment

Additional information

Hydrocarbons, C10-C12, isoalkanes, <2% aromatics, showed no effects on survival, reproduction, or length at nominal and measured concentrations of 0.026 and 0.025 mg/L, respectively. Therefore, the 21-Day No Observed Effect Loading Rate (NOELR) and No Observed Effect Concentration (NOEC) values are 0.026 and 0.025 mg/L, respectively, for these endpoints based upon nominal loading rates and measured (geometric means) concentrations. In a second 21-day study, the adult daphnids exposed to hydrocarbons, C10-C12, isoalkanes, <2% aromatics, at a loading rate of 1 mg/L produced significantly fewer (<0.05) live offspring per adult than the adult daphnids in the control media. Therefore, the 21-day NOELR for reproduction was reported as <1 mg/L. There was 10% immobility of parents in the treatment solution, which was equivalent to the control mortality, therefore the EL50 can be reported as >1 mg/L. In a third study, the hydrocarbons, C13 -C16, isoalkanes, cyclics, <2% aromatics, Daphnia magna, 21 -day EL50 value based on adult immobilization and reduction in reproduction was >5 mg/L. The hydrocarbons, C13 -C16, isoalkanes, cyclics, <2% aromatics, Daphnia magna, 21 -day No Observed Effect Loading Rate (NOELR) based on adult immobilization and reduction in reproduction was 5 mg/L. The data from these studies are used as read-across data to Raffinates (Fischer-Tropsch), C10-C25-branched hydrocarbon fluids.