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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

NOEC (14d) = 18 mg/L (activated sludge; OECD 301B)

Key value for chemical safety assessment

Additional information

Since no studies on the toxicity to aquatic microorganisms are available a ready biodegradability study is used to derive a NOEC for the toxicity to aquatic microorganisms. If a compound degrades well in a ready biodegradability test, or does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value. This approach is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b: Endpoint specific guidance, ECHA 2012b).

Percentage biodegradation in the toxicity controls of an OECD 301B test using 18 mg/L test material on Day 14 was 39% and 14% in two experiments, respectively, thus only in experiment 1 the 25% threshold for inhibition was met (Desmares-Koopmans, 2013). However, one of the test bottles reached 60% biodegradation, which indicated that the test substance did not inhibit microbial activity. Therefore it was concluded, that Multi constituent ester of pentaerythritol 2-ethylhexanoate was found not to inhibit microbial activity.