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Physical & Chemical properties

Particle size distribution (Granulometry)

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Administrative data

Link to relevant study record(s)

Description of key information

Results as reported in one key study; BMS-587319-03: Determination of General Physico-Chemical Properties 

Additional information

The method used is based on a procedure designed to be compatible with that given in European Commission Guidance Document EUR 20268 EN 'Determination of Particle Size Distribution, Fibre Length and Diameter Distribution of Chemical Substances' of 2002.

Conclusion

Particle size data acquired for the test item is shown in the following table:

 

 

Measurement

Method

Result

Proportion of test item having an inhalable particle size <100 µm

Sieve

70.9 %

Proportion of test item having a thoracic particle size <10.0 µm

Cascade Impactor

0.255 %

Proportion of test item having a respirable particle size <5.5 µm

Cascade Impactor

0.076 %