Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation: in vivo (non-LLNA)
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable source; detailed documentation not available

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method B.6 (Skin Sensitisation)
GLP compliance:
not specified
Type of study:
guinea pig maximisation test

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-3-(propan-2-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one
EC Number:
689-404-1
Cas Number:
96240-10-7
Molecular formula:
C5H10N4O
IUPAC Name:
4-amino-3-(propan-2-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one

In vivo test system

Test animals

Species:
guinea pig
Strain:
not specified
Sex:
female

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Under test conditions the TS exhibits no skin-sensitization potential.