Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 939-173-0 | CAS number: -
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline study
Data source
Materials and methods
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- Cas Number:
- 208711-51-7
- Molecular formula:
- C9H9NO2
- IUPAC Name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- Reference substance name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
- IUPAC Name:
- (3Z)-1-benzofuran-3(2H)-one O-methyloxime
Constituent 1
Constituent 2
Method
Species / strain
- Species / strain / cell type:
- other: sat TA 98, TA 100, TA 102, TA 1535, TA 1537
- Metabolic activation:
- with and without
- Metabolic activation system:
- Aroclor rat liver S9-mix
Results and discussion
Test resultsopen allclose all
- Species / strain:
- other: sat TA 98, TA 100, TA 102, TA 1535, TA 1537
- Metabolic activation:
- with
- Genotoxicity:
- positive
- Remarks:
- weak positive effect on strain TA 1537
- Species / strain:
- other: sat TA 98, TA 100, TA 102, TA 1535, TA 1537
- Metabolic activation:
- without
- Genotoxicity:
- negative
- Remarks on result:
- other: all strains/cell types tested
- Remarks:
- Migrated from field 'Test system'.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
positive with metabolic activation
negative without metabolic activation
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