Registration Dossier
Registration Dossier
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EC number: 204-336-0 | CAS number: 119-60-8
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The substance is in the Applicability Domain (AD) of the model.
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- publication
- Title:
- Skin Sensitisation model (CAESAR) (version 2.1.3)
- Author:
- Laboratory of Environmental Chemistry and Toxicology of Mario Negri Institute of Pharmacological Research.
- Bibliographic source:
- VegaNIC v.1.0.6
- Report date:
- 2013
Materials and methods
Test guideline
- Guideline:
- other: REACH guidance on QSARs R6, May 2008
- Principles of method if other than guideline:
- General model for estimating the skin sensitisation.
Test material
- Reference substance name:
- Dicyclohexyl ketone
- EC Number:
- 204-336-0
- EC Name:
- Dicyclohexyl ketone
- Cas Number:
- 119-60-8
- Molecular formula:
- C13H22O
- IUPAC Name:
- dicyclohexyl ketone
- Details on test material:
- SMILE: O=C(C1CCCCC1)C2CCCCC2
InChI: InChI=1/C13H22O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h11-12H,1-10H2
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The prediction indicates that the substance is sensitizer.
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