Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 701-085-3 | CAS number: -
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- HYPOTHESIS FOR THE ANALOGUE APPROACH
Target and source substances belong to the family of silicates. Silicates are known to be practically non-toxic as can be seen on the ECHA website for the source substances. Target and source substances only differ with respect to their morphology. They only differ on the microscopic level. However, this does not alter the substance properties of source substances and target substance at the macroscopic level. For further details please refer to the read across justification under IUCLID section 13.
Cross-reference
- Reason / purpose for cross-reference:
- read-across source
Reference
- Endpoint:
- skin sensitisation, other
- Type of information:
- not specified
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- according to guideline
- Guideline:
- other: not specified
- GLP compliance:
- not specified
- Type of study:
- not specified
- Key result
- Remarks on result:
- no indication of skin sensitisation
Data source
Materials and methods
Test material
- Reference substance name:
- Hydrothermal synthesis product of calcium oxide, quartz and water
- EC Number:
- 701-085-3
- Molecular formula:
- Not applicable for UVCB substance
- IUPAC Name:
- Hydrothermal synthesis product of calcium oxide, quartz and water
- Test material form:
- solid
Constituent 1
Results and discussion
In vivo (non-LLNA)
Results
- Key result
- Remarks on result:
- no indication of skin sensitisation
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
