Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 806-599-2 | CAS number: 33125-90-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
Two QSAR studies have been reported to support the weigh of evidence approach on the identification of potential developmental toxicity of this compound.
Toxicity to reproduction: other studies
Additional information
Results obtained from these two studies suggest a potential developmental toxicity of this compound based both on calculation (TEST) and on structural analogue QSAR (VEGA).
Because of corticosteroids are well known to have adverse effects on developmental toxicity, these two reliable and literature known models have been evaluated to assess the potential toxicity of the compound for the purpose of classification and labelling, and risk assessment under REACh Regulation (1907/2006/CE).
Justification for classification or non-classification
As suggested in the weigh of evidence approach, the substance is classified as potential develplmental toxicant.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
