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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Not irritating to skin/eye/respiratory trac

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

There are no experimental and/or literature specific data on L-CARNITINEAMIDE D-CAMPHORATED.

The analysis was carried out by calculation tools, but results were not exhaustive, since it is a salt, public programs are outside the application field and can not be used. Therefore it has been evaluated the comparison with the base (Camphor; CAS: 76 -22 -2; EC: 200 -945 -0) and the counter-ion (Levocarnitine; CAS: 541 -15 -1; EC: 208 -768 -0) of the substance properties.

Camphor is an eye, skin and respiratory irritant; in particular about eye irritation it was reported to cause flickering, darkening or veiling of vision along with noises in the ears; corneal erosions have been reported in association with the use of inhalant capsules containing camphor [*6 -7].

Nevertheless the irritating properties of Camphor are not expected to be characterizing also for L-Carnitineanide D-Camphorated, because the counter-ion neutralizes the acid component, decreasing possibile irritating properties.

Any details about data available are reported in the report attached at the point 13: Assessment Report.


[*]Secondary source: Hazardous Substances Data Bank – HSDB - U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894, National Institutes of Health, Department of Health & Human Services

[6] National Poisons Information Service Center, United Kingdom; Poisons Information Monograph: Camphor. (March 1996). Available from, as of February 6, 2004: **PEER REVIEWED**

[7] IPCS, CEC; International Chemical Safety Card on Camphor. (Date of review: May 2003). Available from, as of February 5, 2004: **PEER REVIEWED**

Justification for classification or non-classification

Based on evidences determinated by the structure and chemical/physical properties, the L-Carnitineanide D-Camphorated is not expected to be irritant to skin/eye/respiratory tract.

According to the Regulation EC1272/2008 (CLP) L-Carnitineamide D-Camphorated is classified as non irritant.