Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
No abnormal clinical signs, lymph node weight or body weight were observed in any of the animals throughout the study period.
The sensitisation potential of E-Y110 was assessed in 30 female mice using the LLNA study performed according to OECD 429. E-Y110 was suspended in a mixture of acetone/olive oil (4:1) to make three concentrations of test substance: 5, 15 and 50 w/v%. HCA 25 v/v% was used as positive control and the vehicle was used as negative control. The SI values were 1.13, 0.90 and 0.83 in the 5, 15 and 50 w/v% test substance groups, respectively. The SI value of HCA was 6.68. No abnormalities in body weight, lymph node weight or clinical signs were observed in any of the animals. From the results, it is concluded that E-Y110 has no sensitisation potential under the conditions of this study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again