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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The  lowest reliable long-term fish studies for Pimephales promelas which are reported by  Kimball, G.1978, after a 28-days  exposure to aluminium sulphate  induced no mortality effects below 44.9 mg/l (NOEC).
This information will be take into account for acute fish toxicity for the derivation of PNEC.
The available data for saltwater fishes are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor10 to extrapolate to EC10/LC10 or NOEC  following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment” and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa.
The lack of reliable long-term saltwater toxicity data means that an annual average concentration must currently be based upon the freshwater NOEC (Pimephales promelas of 44.9 mg/l with an assessment factor of 10). NOEC for marine water intertebrates will be 4.5 mg/l.
This information will be take into account for acute fish toxicity for the derivation of PNEC.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
44.9 mg/L

Marine water fish

Marine water fish
Effect concentration:
4.5 mg/L

Additional information

Under the conditions of the study of Kimball, G.1978, aluminium sulphate induced no mortality effects in Pimephales promelas below 44.9 mg/l (NOEC) expressed as aluminium sulphate.

 

The available data for saltwater fishes are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor10 to extrapolate to EC10/LC10 or NOEC  followingthe “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment” and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa.