Registration Dossier
Registration Dossier
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EC number: 233-135-0 | CAS number: 10043-01-3
Bioaccumulation: terrestrial
Administrative data
Link to relevant study record(s)
Description of key information
According to “ANNEX IX- STANDARD INFORMATION REQUIREMENTS FOR SUBSTANCES MANUFACTURED OR IMPORTED IN QUANTITIES OF 100 TONNES OR MORE , a bioaccumulation study need not be conducted if:
— the substance has a low potential for bioaccumulation (for instance a log Kow ≤ 3) and/or a low potential to cross biological membranes, or
— direct and indirect exposure of the aquatic compartment is unlikely.
The estimated Log BCF of Aluminium sulphate is 0.5 (BCF = 3.162 L/kg wet-wt)
This substance has a limited potential to bioaccumulate (based on log Kow used :, Log Kow estimated : -5.08 , and predicted bioconcentration factors, log BCF = 0.500 (EPIWIN/BCF Program).
The estimated BCF of 3.162 L/kg wet-wt was measured by calculation from EPI SuiteTM v4.1 Program.
These values would suggest very low bioaccumulation potential.
Key value for chemical safety assessment
- BCF (terrestrial species):
- 3.162 L/kg ww
Additional information
According to “ANNEX IX- STANDARD INFORMATION REQUIREMENTS FOR SUBSTANCES MANUFACTURED OR IMPORTED IN QUANTITIES OF 100 TONNES OR MORE , a bioaccumulation study need not be conducted if:
— the substance has a low potential for bioaccumulation (for instance a log Kow ≤ 3) and/or a low potential to cross biological membranes, or
— direct and indirect exposure of the aquatic compartment is unlikely.
The estimated Log BCF of Aluminium sulphate is 0.5 (BCF = 3.162 L/kg wet-wt)
This substance has a limited potential to bioaccumulate (based on log Kow used :, Log Kow estimated : -5.08 , and predicted bioconcentration factors, log BCF = 0.500 (EPIWIN/BCF Program).
The estimated BCF of 3.162 L/kg wet-wt was measured by calculation from EPI SuiteTM v4.1 Program.
These values would suggest very low bioaccumulation potential.
This is Exposure Assessment Tools and Models made from EPA (Environmental Protection Agency).
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Whole Body Primary Biotransformation Rate Estimate for Fish:
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------+-----+--------------------------------------------+---------+---------
TYPE | NUM | LOG BIOTRANSFORMATION FRAGMENT DESCRIPTION | COEFF | VALUE
------+-----+--------------------------------------------+---------+---------
L Kow| * | Log Kow = -5.08 (KowWin estimate) | 0.3073 | -1.5598
MolWt| * | Molecular Weight Parameter | | -0.8877
Const| * | Equation Constant | | -1.5058
============+============================================+=========+=========
RESULT | LOG Bio Half-Life (days) | | -3.9846
RESULT | Bio Half-Life (days) | |0.0001036
NOTE | Bio Half-Life Normalized to 10 g fish at 15 deg C |
============+============================================+=========+=========
Biotransformation Rate Constant:
kM (Rate Constant): 125 /day (10 gram fish) **
kM (Rate Constant): 70.29 /day (100 gram fish) **
kM (Rate Constant): 39.53 /day (1 kg fish) **
kM (Rate Constant): 22.23 /day (10 kg fish) **
** Predicted value exceeds theoretical whole body maximum value.
kM (Rate Constant) of 125 /day is recommended/applied for 10 g fish
Arnot-Gobas BCF & BAF Methods (including biotransformation rate estimates):
Estimated Log BCF (upper trophic) = -0.049 (BCF = 0.893 L/kg wet-wt)
Estimated Log BAF (upper trophic) = -0.049 (BAF = 0.893 L/kg wet-wt)
Estimated Log BCF (mid trophic) = -0.031 (BCF = 0.9315 L/kg wet-wt)
Estimated Log BAF (mid trophic) = -0.031 (BAF = 0.9315 L/kg wet-wt)
Estimated Log BCF (lower trophic) = -0.027 (BCF = 0.9402 L/kg wet-wt)
Estimated Log BAF (lower trophic) = -0.027 (BAF = 0.9402 L/kg wet-wt)
Arnot-Gobas BCF & BAF Methods (assuming a biotransformation rate of zero):
Estimated Log BCF (upper trophic) = -0.049 (BCF = 0.893 L/kg wet-wt)
Estimated Log BAF (upper trophic) = -0.049 (BAF = 0.893 L/kg wet-wt)
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