Registration Dossier
Registration Dossier
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EC number: 233-135-0 | CAS number: 10043-01-3
Endpoint summary
Administrative data
Description of key information
Additional information
Aluminium sulphate will bioaccumulate in aquatic and terrestrial species
Numerous field and laboratory studies have demonstrated that fish accumulate aluminum (as aluminium sulphate) in and on the gill. It has been suggested that the rate of transfer of aluminum (as aluminium sulphate) into the body of fish is either slow or negligible under natural environmental conditions . The initial uptake of aluminum (as aluminium sulphate) by fish essentially takes place not on the gill surface but mainly on the gill mucous layer.
Fish may rapidly eliminate mucus and the bound aluminum following the exposure episode.There wasfound that depuration of aluminum from the gills of Atlantic salmon (Salmo salar) was extremely rapid once fish were transferred into clean water. The authors suggested that the rapid loss is due to expulsion of aluminum bound to mucus.
In Atlantic salmon (Salmo salar), steady state BCFs of 76 and 190 were reported after a 60-day exposure and BCFs of 362 after a45-day exposure to aluminium (aluminium sulphate) at pH 5.6 to 5.8.
A BCF of 155 has also been reported in rainbow trout (Oncorhynchus mykiss) gill tissue after a 3-day exposure to aluminium (as aluminium sulphate).
Steady-state BCF values as high as 14,000 have been reported in Asellus aquaticus after a 20-day exposure to aluminium (as aluminium sulphate). However, much of the accumulation was due to passive adsorption of aluminium onto the cuticle. Therefore, these BCFs are not representative of the internal concentration of aluminium and over estimate accumulation in this species.
A steady state BCF of 19,000 has been reported for the gut tissue of the fresh water snail Lymnaea stagnalis. However, the gut of the snail contains mucus that has a high affinity for metals such as aluminium. The mucus can be excreted and may be a primary route for the removal of metals from the snails. It was reported that mucus may have remained during the analysis of the gut and so this BCF may overestimate the accumulation of aluminium A BCF of 155 has also been reported in rainbow trout (Oncorhynchus mykiss) gill tissue after a 3-day exposure to aluminium (as aluminium sulphate) in this species.
A BCF of 0.13 to 0.5 in the whole body for the snail Helix aspersa has been reported.
BCFs for terrestrial plants were calculated based on data cited in the review by Bélanger et al. (1999). For both hardwood and coniferous species, the calculated BCF ranged from 5 to 1,300 for foliage and from 20 to 79,600 for roots in studies done with aluminum solutions. For those conducted with soil, BCFs were lower for both foliage (0.03–1.3) and roots (325–3,526). BCFs calculated for grain and forage crops ranged from 4 to 1,260 infoliage and from 200 to 6,000 in roots for experiments done with solutions. For soil experiments, the foliar BCF varied from 0.07 to 0.7.
The estimated BCF of 3.16 L/kg wet-wt was measured by calculation from EPI SuiteTM v4.0 Program. This is Exposure Assessment Tools and Models made from EPA (Environmental Protection Agency) .
BCFBAF Program (v3.00) Results:
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SMILES : [Al](O)S(=O)(=O)O(=O)S(O(=O))(=O)=OS(O([Al]))(=O)=O
CHEM :aluminium sulphate
MOL FOR: H4 O12 S3 Al2
MOL WT : 346.17
--------------------------------- BCFBAF v3.00 --------------------------------
Summary Results:
Log BCF (regression-based estimate): 0.50 (BCF = 3.16 L/kg wet-wt)
Biotransformation Half-Life (days) : 1.48e-005 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): -0.05 (BAF = 0.893 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: -7.82
Equation Used to Make BCF estimate:
Log BCF = 0.50
Correction(s): Value
Correction Factors Not Used for Log Kow < 1
Estimated Log BCF = 0.500 (BCF = 3.162 L/kg wet-wt)
The estimated BCF (upper trophic) of 0.893 L/kgwet-wt was measured by calculation from EPI SuiteTM v4.0 Program. This is Exposure Assessment Tools and Models made from EPA (Environmental Protection Agency) .
Summary Results:
Log BCF (regression-based estimate): 0.50 (BCF = 3.16 L/kg wet-wt)
Biotransformation Half-Life (days) : 1.48e-005 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): -0.05 (BAF = 0.893 L/kg wet-wt)
Log Kow (experimental): not available from database
Log Kow used by BCF estimates: -7.82
Equation Used to Make BCF estimate:Log BCF = 0.50
Correction(s): Value
Correction Factors Not Used for Log Kow < 1
Estimated Log BCF (upper trophic) = -0.049 (BCF = 0.893 L/kg wet-wt)
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