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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
surface tension
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Modern study peformed under GLP and using the recommended method, EC directive 92/69/EEC, A.5.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.5 (Surface Tension)
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes
Type of method:
ring method

Test material

Constituent 1
Reference substance name:
PTH-decahydroamide
IUPAC Name:
PTH-decahydroamide
Constituent 2
Reference substance name:
Ro 31-9373/000
IUPAC Name:
Ro 31-9373/000
Details on test material:
The test material received from F. Hoffmann-La Roche Ltd was a white solid powder from lot no. 25927 with a purity of 99.8%.

Results and discussion

Surface tension
Surface tension:
51.9 mN/m
Temp.:
20 °C
Conc.:
1 g/L

Any other information on results incl. tables

The gauging factor (C) was determined to be 1.01. Four consecutive measurements were performed on the 1.0 g/L solution of PTH-Decahydroamide and the gauging factor applied to get the corrected surface tension. A constant value of 51.9 mN/m at 20 °C was determined for the corrected surface tension.

Equilibration Time at 20 ⁰C (minutes)

Measured Surface Tension (mN/m)

Corrected Surface Tension (mN/m)

10

52.65

51.9

15

52.65

51.9

25

52.65

51.9

40

52.65

51.9

Average

51.9

Std. Dev.

0.0 (n=4)

Based on the criteria as outlined in the EC guideline A.5, it is concluded that PTH-decahydroamide (Ro 319373/000) should be regarded as a surface active material.

Applicant's summary and conclusion

Conclusions:
The surface tension of a 1 g/L solution of PTH-decahydroamide (Ro 31 -9373/000) was determined to be 51.9 mN/m. Based on the criteria as outlined in the EC guideline A.5, it was concluded that PTH-decahydroamide (Ro 319373/000) should be regarded as a surface active material.
Executive summary:

The determination of the surface tension of an aqueous solution of PTH-decahydroamide (Ro 31 -9373/000) was performed using EC directive 92/69/EEC, A.5 (1992).

The surface tension of a 1 g/L solution of PTH-decahydroamide (Ro 31 -9373/000) was determined to be 51.9 mN/m. Based on the criteria as outlined in the EC guideline A.5, it was concluded that PTH-decahydroamid (Ro 319373/000) should be regarded as a surface active material.

This conclusion is in agreement with the foaming phenomenon observed when PTH-decahydroamide (Ro 31 -9373/000) is strongly agitated in aquoeus solutions.