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EC number: 413-610-0 | CAS number: 124172-53-8 LICHTSCHUTZMITTEL 1736
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP - Guideline study.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 471/ 84/449/EWG B.14/ Ames-Test
- GLP compliance:
- yes
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
- EC Number:
- 413-610-0
- EC Name:
- N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
- Cas Number:
- 124172-53-8
- Molecular formula:
- C26H50N4O2
- IUPAC Name:
- N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
Constituent 1
Method
Species / strain
- Species / strain / cell type:
- bacteria, other: sat TA98,100,1535,1537
- Metabolic activation system:
- Aroclor-induced rat liver S9 mix
- Test concentrations with justification for top dose:
- Concentration range in the main test (with metabolic activation): 20 ... 5000µg/plate
Concentration range in the main test (without metabolic activation): 20 ... 5000µg/plate - Vehicle / solvent:
- Solvent: DMSO
Results and discussion
Any other information on results incl. tables
Comments:
For the bacterial toxic concentration
b) imHaupt-TestohnemetablischeAktivierungnurmitTA98 imPrinkuloationstestbei5000myg/Platte
KonzentrationderTestsubstanz, beiderAusfllungauftritt :GallstndigeLslichkeit
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative with metabolic activation
negative without metabolic activation
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