Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Comparable to guideline study with acceptable restrictions.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: ATC-Methode (Acute Toxic Class Methode) E.Schlede, U.Mischke R.RoII, D.Kayser: "A national validation study of the acute- toxic-class methode..…” Arch. Toxicol. 66: 455-470 (1992)
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
EC Number:
413-610-0
EC Name:
N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide
Cas Number:
124172-53-8
Molecular formula:
C26H50N4O2
IUPAC Name:
N,N'-1,6-hexanediylbis(N-(2,2,6,6-tetramethyl-piperidin-4-yl)formamide

Test animals

Species:
other: rat,Wistar

Administration / exposure

Vehicle:
other: Suspension in Olive oil DAB 9

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 200 mg/kg bw
Mortality:
Male:2200mg/kg bw; Number of animals:3; Number of deaths: 0
Female:2200mg/kg bw, Number of animals:3; Number of deaths:0
Gross pathology:
Effects on organs:
No pathological findings

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU