Registration Dossier
Registration Dossier
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EC number: 700-862-4 | CAS number: 42797-18-2
Endpoint summary
Administrative data
Description of key information
From the results of both the skin and eye irriation studies on 2-(4Phenylbenzoyl)benzoic acid, the test item does not meet the criteria for classification according to the Globally Harmonized System of Classification and Labelling of Chemicals.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The test item produced a primary irritation index of 0.0 and was classified as non-irritant to rabbit skin according to the Draize classification scheme. No corrosive effects were noted.
The test item produced a maximum group mean score of 9.0 and was classified as a mild irritant (Class 4 on a 1 to 8 scale) to the rabbit eye according to a modified Kay and Calandra classification system.
The test item does not meet the criteria for classification according to the Globally Harmonized System of Classification and Labelling of Chemicals.
Justification for selection of skin irritation / corrosion endpoint:
this in vivo study confirmed the results of the in vitro testing
Justification for selection of eye irritation endpoint:
The in vitro results didn't allow classification the substance.
Effects on eye irritation: slightly irritating
Justification for classification or non-classification
The test item does not meet the criteria for classification according to the Global lyHarmonized System of Classification and Labelling of Chemicals.
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