Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In a Guinea pig maximization test (GPMT) performed according to OECD TG 406 with 10 animals in control and treament groups each, the test substance, suspended in Miglyol 812, revealed a negative result. Intradermal induction concentration was chosen with 5 % followed by a topical induction concentration of 25 %. Challenge was performed by topical treatment with a 12.5% suspension in Miglyol 812.

Based on this study the test item does not possess a skin sensitizing effect in Guinea pigs.


Migrated from Short description of key information:
Skin Sensitisation, Maximization Test according to Magnusson and Kligman (Guinea pig, GLP, comparable to OECD TG 406): not sensitizing

Justification for selection of skin sensitisation endpoint:
only one study available

Justification for classification or non-classification

Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.