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EC number: 418-570-8
CAS number: 25383-07-7
Phenethylammonium salt of fosfomycin is an
organic salt, freely soluble in water, which dissociates into fosfomycin
((3-methyloxiran-2-yl) phosphonic acid)) and phenethylammonium ions
within the environmentally relevant pH range (5-8). Experimental
Log Koc for phenethylammonium is 4.54. Fosfomyc
in anion has
weak UV absorption and was not detectable at the selected wavelenght in
the absorption study,
then its Koc has been estimated by KOCWIN v2.00 (US EPA): calculated
values of Log Koc for non-ionized fosfomycin are 0.09 (estimate from Log
Kow) and 0.07 (estimate from MCI); Koc value for fosfomycin anion is not
expected to be significantly different from its non-ionized form.
High mobility in soil is therefore expected
for the fosfomycin anion, while pour mobility is expected for
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