Registration Dossier
Registration Dossier
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EC number: 227-114-5 | CAS number: 5661-03-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study was perfomed according GLP practices, but as a screening test and without analytical monitoring. Therefore, the test do not totally comply with the specific guideline but is well documented and scientifically acceptable. For this reason, we consider this study as Klimish 2.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Octahydrocyclopenta[c]pyrrole
- EC Number:
- 227-114-5
- EC Name:
- Octahydrocyclopenta[c]pyrrole
- Cas Number:
- 5661-03-0
- Molecular formula:
- C7H13N
- IUPAC Name:
- octahydrocyclopenta[c]pyrrole
- Details on test material:
- Colourless liquid, stable, soluble in water, stored at room temperature.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- 21-25°C
- pH:
- between 7.9 and 9.
- Details on test conditions:
- Lighting 4440-8880 Lux ;
Duration 72 hours - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
Results and discussion
Any other information on results incl. tables
Microscopical observation
in the following table the appearance of the laga at the end of the test were stated :
| Nom. Conc. in mg/L | Observation |
| 0 | normal growth |
| 1 | normal growth |
| 10 | fewer cells |
| 100 | no cells |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- In treatment 10 mg/L significant inhibition could be observed. Therefore, the concentration 1 mg/L is stated as NOEC.
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