Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Acute Fish Toxicity:

The water accommodated fraction of hydrocarbons, C12-C16, isoalkanes, cyclics, <2% aromatics, produced a 96-hour LL50 value of >87,556 mg/L and LL0 value of 87,556 mg/L to the fish, Oncorhynchus mykiss. No mortality was observed in either the control or treatment systems. These data are used as read-across data to hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics.

Additional data from a read-across substance supports that hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics does not cause acute aquatic toxicity to fish. The water accommodated fraction of hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics, produced a 96-hour LL50 value of >250 mg/L and LL0 value of 250 mg/L with Danio rerio (Ex-Brachydanio rerio). No mortality was observed in either the control or treatment systems. Although these two substances are analogs to hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, they have considerable overlap in carbon number. Additionally, although the second analog also contains normal hydrocarbons, which are not found in hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, because their toxicological mode of action is the same as isoalkanes and cycloalkanes, they would be expected to exhibit the same degree of toxicity - or in this case, the lack of acute toxic effects.

Chronic Fish Toxicity:

The hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, estimated freshwater fish 28-day NOELR (No Observed Effect Loading Rate) value is >1000 mg/l based on growth. Based on these data, hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, are not expected to produce chronic toxic effects to fish at saturation.

Acute Invertebrate Toxicity:

The water accommodated fraction (WAF) of hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics, did not produce a 50% effect (immobility) with Daphnia magna at a loading of 1000 mg/L after a 48-hour exposure. Therefore, the 48-hour LL50 is reported as >1000 mg/L. There was no mortality at the 1000 mg/L loading level after 48 hours. Therefore, the 48-hour LL0 for mortality is reported as 1000 mg/L. There was also no mortality in the control. These data are used as read-across data to hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics.

The water accommodated fraction (WAF) of hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics, did not produce a 50% effect (mortality) with Chaetogammarus marinus at a loading of 10,000 mg/L after a 96-hour exposure. Therefore, the 96-hour LL50 is reported as >10,000 mg/L. There was no mortality at the 10,000 mg/L loading level after 96 hours. Therefore, the 96-hour NOELR for mortality is reported as 10,000 mg/L. There was also no mortality in the control. These data are used as read-across data to hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics. Although these analogs also contain normal hydrocarbons, which are not found in hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, because their toxicological mode of action is the same as isoalkanes and cycloalkanes, and their hydrocarbon constituents have even less water solubility and consequently lower aqueous concentration, they would be expected to exhibit the same degree of toxicity - or in this case, the lack of acute toxic effects.

Based on these data, hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, are not expected to produce acute toxic effects to invertebrates at saturation.

Chronic Invertebrate Toxicity:

The hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics, Daphnia magna, 21-day EL50 value based on adult immobilization and reduction in reproduction was >5 mg/L. The hydrocarbons, C13-C16, isoalkanes, cyclics, <2% aromatics, Daphnia magna, 21-day No Observed Effect Loading Rate (NOELR) based on adult immobilization and reduction in reproduction was 5 mg/L. These data are used as read-across data to hydrocarbons, C14 -C19, isoalkanes, cyclics, <2% aromatics. Based on these data, hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, is not expected to produce chronic toxic effects to invertebrates at saturation.

Algal Toxicity:

Growth of an alga culture, Pseudokirchnerella subcapitata (reported as Raphidocelis subcapitata), as measured by biomass and growth rate, exposed to a water accommodated fraction of hydrocarbons, C11-C14, n-alkanes, isoalkanes, cyclics, <2% aromatics, was not inhibited over 72 hours. The growth of algae in the test systems was greater than the controls, which performed normally. Therefore, the 72-hr EL50 values for the two endpoints are reported as >1000 mg/L. The 72-hr NOELR values for biomass and growth rate are reported as 1000 mg/L, respectively. These data are used as read-across to hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics. Based on these data, hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics, is not expected to produce toxic effects to algae at saturation.

Microorganisms Toxicity:

The hydrocarbons, C14-C18, n-alkanes, isoalkanes, cyclics, <2% aromatics, wastewater treatment plant activated sludge respiration inhibition 3h-EL50 value was >100 mg/L. These data are used as read-across data to hydrocarbons, C14-C19, isoalkanes, cyclics, <2% aromatics. Based on these data, hydrocarbons, C14-C19, isoalkanes, cyclics, <2%aromatics, is not expected to produce toxic effects to wastewater treatment organisms at saturation.