Registration Dossier

Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given

Data source

Reference
Reference Type:
publication
Title:
The acute oral toxicity, repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds
Author:
Schafer, E.W., Bowles, W.A. and Hurlbut, J.
Year:
1983
Bibliographic source:
Arch. Environm. Contam. Toxicol. No. 12, p. 355-382

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No specific guideline has been given in the publication; however it has been described that wild-trapped birds were preconditioned to captivity and dosed by gavage according to methods described by DeCino et al. (1966), Schafer (1972) and Schafer et al. (1967).
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-methylhydroquinone
EC Number:
202-443-7
EC Name:
2-methylhydroquinone
Cas Number:
95-71-6
Molecular formula:
C7H8O2
IUPAC Name:
2-methylbenzene-1,4-diol
Dose method:
gavage
Analytical monitoring:
not specified

Test organisms

Test organisms (species):
other: Agelaius phoeniceus
Details on test organisms:
- Handling of birds: wild-trapped birds were preconditioned to captivity for 2 to 6 weeks and were dosed by gavage with solutions of the test chemical in propylene glycol.

Study design

Total exposure duration (if not single dose):
18 h

Results and discussion

Effect levels
Duration (if not single dose):
18 h
Dose descriptor:
LD50
Effect level:
> 148 mg/kg bw
Basis for effect:
mortality

Applicant's summary and conclusion