Registration Dossier
Registration Dossier
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EC number: 214-317-9 | CAS number: 1120-71-4
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In vitro, the substance reacts with DNA.
DNA damages are caused in various organisms, cells, and test systems e.g.
- Mutation is caused by the substance in bacteria and in plant cells.
- Mitotic recombination is caused by the substance in yeast.
- Chromosomal aberrations, sister chromatid exchanges and cell transformation are caused by the substance In cultured mammalian cells.
- DNA strand breaks are caused by the substance in vivo in rat brain cells.
(Based on data compiled by IARC 1999)
Endpoint Conclusion: Adverse effect observed (positive)
Justification for classification or non-classification
classification required (H350)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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