Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation / corrosion
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No guideline followed. Non-GLP. Only secondary source. Only short notice.

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Moreno, O.H. (1973). Report to RIFM, cited in Opdyke (1976).
Bibliographic source:
Food Cosmetic Toxicology, 14, 693-698
Report date:
1973

Materials and methods

Principles of method if other than guideline:
Benraldebyde applied full strength to intact or abraded rabbit skin for 24 hr under occlusion was moderately irritating.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzaldehyde
EC Number:
202-860-4
EC Name:
Benzaldehyde
Cas Number:
100-52-7
Molecular formula:
C7H6O
IUPAC Name:
benzaldehyde

Test animals

Species:
rabbit

Test system

Type of coverage:
occlusive
Preparation of test site:
other: intact or abraded
Duration of treatment / exposure:
24 h

Results and discussion

Any other information on results incl. tables

moderately irritating.

Applicant's summary and conclusion

Interpretation of results:
moderately irritating
Remarks:
Migrated information
Conclusions:
The above presented data are not sufficient for a decission on classification. However, since benzaldehyde is reported to be only moderately irritating to the skin of rabbits and the substance is not legally classified according to Annex VI, CLP, no classification as skin irritant is warranted according to Regulation (EU) 1272/2008 and Directive EU 67/548/EEC, respectively.