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Long-term toxicity to aquatic invertebrates

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Description of key information

Short-term toxicity to aquatic invertebrates of the substance is derived using read across. EC 500-118-7 was determined to result in a 21 day-NOEC >= 10 mg/L.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
10 mg/L

Additional information

Long-term toxixity to aquatic invertebrates was determined in a read across approach with EC 500-118-7.

Hypothesis for the read-across approach:

Group: Reaction mass of Glycerol, propoxylated and Sucrose, propoxylated;Succhrose, propoxylated; Propylidynetrimethanol, propoxylated; Glycerol, propoxylated; DGlucitol, propoxylated; Propane-1,2-diol, propoxylated; Pentaerythritol, propoxylated; 2,2',2''Nitrilotriethanol, propoxylated; Trimethylolpropane, ethoxylated; Diethylene glycol, propoxylated; Ethylene glycol, propoxylated; Diethanolamine, propoxylated.

The substance is member of a group of chemicals with similar chemical structure and physical behaviour:

1.) Chemical similarity: All of these substances have terminal OH-groups and ether-linkages as common structural features. Thus, the substances differ from each other only in the identity/type of starter molecule (aliphatic alcohols with 2 to 8 hydroxy functions) used and its associated bonding with the alkoxylate repeating units. Typically the products are substances with a range of Ethyleneoxide or Propyleneoxide units (1 -12.5) added to starter molecules. All substances are characterised by a molecular weight distribution of ca. 150 - 1000. The common function of the members of the group is to allocate a high number of hydroxy functions which are intended to react with e.g. an isocyanate.

2.) Physical behaviour: All members of the group are liquids with elevated viscosity, high solubility in water (> 100 g/L) and a low vapour pressure (<0.0003 hPa).