Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

As stated in section 5.2.1, Alcohols, C20-30 (even numbered), is a UVCB substance that comprises several linear long chain alcohols, predominantly tetracosan-1-ol (C24), hexacosan-1-ol (C26) and octacosan-1-ol (C28). Together, these constituents make up approximately 70% of the composition of Alcohols, C20-30 (even numbered). Experimental data for the LCA Category was evaluated and trends in the environmental fate of long chain alcohols was used to assess Alcohols, C20-30 (even numbered).


Reliable experimental studies (Klimisch scores 1 and 2) were performed in accordance with OECD Guidelines on eicosan-1-ol (C20), docosan-1-ol (C22), 2-decyltetradecanol (C24) and tetradecyloctadecan-1-ol (C32) that are constituents of and analogous to primary constituents of Alcohols, C20-30 (even numbered) and the LCA Category. The key study by Flach (2014) reported 90% biodegradation of tetradecyloctadecan-1-ol in an OECD 301B CO2-evolution test over 28 days. More than 60% of tetradecyloctadecan-1-ol had degraded within the 10-day study window. The key study demonstrates that tetradecyloctadecan-1-ol, a C32 long chain alcohol, is readily biodegradable. Supporting studies also confirmed the ready biodegradability of LCAs including constituents and analogue constituents of Alcohols, C20-30 (even numbered).


According to Annex IX Column 2 of Regulation (EC) No 1907/2006 REACH concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals an absorption/desorption study does not need to be conducted if the substance and its relevant degradation products decompose rapidly. Nevertheless, predictions using established QSAR indicate log Koc >5.