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EC number: 687-349-8 | CAS number: 173194-95-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: In accordance with OECD and EU protocol and GLP methods..
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- thermal analysis
- Remarks:
- Metal Block Method also uses
Test material
- Reference substance name:
- (6-hydroxynaphthalen-2-yl)boronic acid
- EC Number:
- 687-349-8
- Cas Number:
- 173194-95-1
- Molecular formula:
- C10H9BO3
- IUPAC Name:
- (6-hydroxynaphthalen-2-yl)boronic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name of test material (as cited in study report): Boronic Acid
-Chemical Name: 6-hydroxy-2-naphthaleneboronic acid
- Substance type: off white powder
- Storage condition of test material: room temperatire in the dark (08 to 14 October 2013), Approximately 4°C in the dark (onwards)
Constituent 1
Results and discussion
Melting / freezing point
- Melting / freezing pt.:
- ca. 217 °C
- Decomposition:
- yes
- Decomp. temp.:
- ca. 217 °C
Any other information on results incl. tables
Thermal Analysis:
Thermograms and thermographic data for determinations 1 and 2 are shown in attachment 'Thermogram and Thermographic Data' below. The test item was determined to decompose while melting from approximately 217°C (490K).
Metal Block Method:
Observation times temperatures and test item appearances are shown in attachment 'Metal Block Method Results'. The test item was determined to decompose while melting from approximately 227°C(500K).
Applicant's summary and conclusion
- Conclusions:
- As a result of the low rate of enthalpy change during decomposition/melting, the onset temperature could only be approximated during thermal analysis.
The thermal analysis onset temperature has been reported as the definitive result as it represents the worst case scenario with respect to thermal stability. Also, the procedure utilized a standardized heating rate of 1 °C/min, compatible with the guidelines.
Visual assessment of the test item during the metal block evaluation confirmed that the thermal analysis endotherm at approximately 156 °C did not originate from a phase transition, but was attributed to the loss of a volatile component/impurity.
The test item, Boronic Acid was determined to decompose while melting from approximately 217°C (490 K).
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