Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 400-100-8 | CAS number: 84057-97-6 BLEU N-RM 2114; BLEU NYLOSAN N-BLN; BLUE N-RM 2114; NYLOSAN BLAU N-BLN; NYLOSAN BLEU N-BLN; NYLOSAN BLUE N-BLN
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Only data summary seen from SNIF docs
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method B.1 (Acute Toxicity (Oral))
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- no
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Doses:
- Single dose 5000 mg/kg
- No. of animals per sex per dose:
- 5 males and 5 females
- Preliminary study:
- not classified
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Conclusions:
- Data obtained through ECHA Inquiry under the 12 year rule.
- Executive summary:
Data obtained through ECHA Inquiry under the 12 year rule.
Reference
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 5 000 mg/kg bw
Acute toxicity: via dermal route
Link to relevant study records
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Only data summary seen from SNIF docs
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method B.3 (Acute Toxicity (Dermal))
- Principles of method if other than guideline:
- other guideline: method B3
- GLP compliance:
- yes
- Preliminary study:
- Comments:
4103 PERCUT LD50: >2000 mg/kg - Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Conclusions:
- Data obtained through ECHA Inquiry under the 12 year rule.
- Executive summary:
Data obtained through ECHA Inquiry under the 12 year rule.
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
