Registration Dossier
Registration Dossier
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EC number: 203-716-3 | CAS number: 109-89-7
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Aquatic toxicological aspects of dithiocarbamates and related compunds. I. Short-term toxicity tests.
- Author:
- van Leeuwen CJ, Maas-Diepeveen JL, Niebeek G, Vergouw WHA, Griffioen NPS and Luijken MW
- Year:
- 1 985
- Bibliographic source:
- Aquatic Toxicology, 7: 145-164
- Reference Type:
- other: thesie
- Title:
- Ecotoxicologigal aspects of dithiocarbamates
- Author:
- van Leeuwen CJ
- Year:
- 1 986
- Bibliographic source:
- Thesis University of Utrecht
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- Aquatic Toxicology, 7: 145-164
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Diethylamine
- EC Number:
- 203-716-3
- EC Name:
- Diethylamine
- Cas Number:
- 109-89-7
- Molecular formula:
- C4H11N
- IUPAC Name:
- diethylamine
- Details on test material:
- - Name of test material (as cited in study report): Sodium diethyldithiocarbamate (NaDEDC)
- Supplier: Fluka AG (Buchs, Switzerland)
- Purity: 99%
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
PHYSICO-CHEMICAL PROPERTIES
- Water solubility: very well soluble
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Details on test conditions:
- TEST SYSTEM
The stock solutions were prepared fresh each day. The test solutions were renewed daily.
TEST MEDIUM / WATER PARAMETERS
- Detailed information about the chemical composition of the media is given elsewhere (Van Leeuwen and Maas, 1985).
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 56 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: Confidence limit: 32.0 100 mg/l
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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