Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed OECD study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Purity: 98.8 %

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2
Temp.:
23 °C
pH:
ca. 8.5
Details on results:
determ. no. stock solution water test substance test substance
[ml] [ml] conc. in n-octanol conc. in water log Pow
[mg/l] [mg/l]

A1 5 10 704,5 8,19 1,9
A2 5 10 716,8 6,47 2,0
B1 10 10 716,5 7,49 2,0
B2 10 10 726,5 11,71 1,8
C1 20 10 728,1 5,27 2,1
C2 20 10 731,3 6,73 2,0
mean --- --- --- --- 2,0

Recovery rate: 99 - 102 %

Applicant's summary and conclusion

Conclusions:
The LogPow of the substance is 2.0 at 23°C.
Executive summary:

The Log Pow of the substance was determined according to OECD guideline 107 with the shake flask method and was found to be 2.0 at 23°C.