Registration Dossier

Administrative data

Description of key information

Skin irritation: not irritant
Eye irritation: irritant du to redness, chemosis and corneal opacity

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

EUF was tested undiluted for primary skin reactions. In the most recently performed study (from 2008), no signs of irritation were observed. Therefore, no classification is required for skin irritation

In an eye irritation study (2008), EUF induced eye irritations, which were most likely due to the irritating properties of formaldehyde. No such effects can be expected from either ethylene glycol or urea respectively.


Effects on eye irritation: irritating

Justification for classification or non-classification

EUF induced corneal opacity as well as redness and chemosis of the conjunctiva. Proposal for classification and labelling of EUF according to Directive 67/548/EEC:

Xi, R 36 – irritating to eyes.