Registration Dossier
Registration Dossier
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EC number: 412-770-9 | CAS number: 12141-67-2 NATRIUMMETAWOLFRAMAT
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 84/449/EC, B.5
- GLP compliance:
- yes
Test material
- Reference substance name:
- Hexasodium tungstate hydrate
- EC Number:
- 412-770-9
- EC Name:
- Hexasodium tungstate hydrate
- Cas Number:
- 12141-67-2
- Molecular formula:
- Na6 H2 W12 O40 . xH2O
- IUPAC Name:
- hydrate hydrogen oxygen sodium hydride tungsten
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Vehicle:
- not specified
- Amount / concentration applied:
- 100 mg
- Number of animals or in vitro replicates:
- 6
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- conjunctivae score
- Basis:
- mean
- Score:
- 2.3
- Max. score:
- 3
- Remarks on result:
- other: Max. duration: h; Max. value at end of observation period: 1
- Irritation parameter:
- chemosis score
- Basis:
- mean
- Score:
- 1.3
- Max. score:
- 2
- Remarks on result:
- other: Max. duration: h; Max. value at end of observation period: 0
- Irritation parameter:
- cornea opacity score
- Basis:
- mean
- Score:
- 0
- Max. score:
- 0
- Remarks on result:
- other: Max. duration: h;Max. value at end of observation period: 2
- Irritation parameter:
- iris score
- Basis:
- mean
- Score:
- 0
- Max. score:
- 0
- Remarks on result:
- other: Max. duration: h; Max. value at end of observation period: 0
Applicant's summary and conclusion
- Interpretation of results:
- irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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