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EC number: 700-579-6 | CAS number: -
Maximal irritating concentration was determined to be 60 % in olive oil
Maximum Non-irritating Concentration was determined to be 60 % in olive oil
vehicle : olive oil
Skin reaction as a function of time and concentration
0: no visible modification
Weight of a animals were recorded for controls and tested groups. No difference was noticed
The aim of the study was to assess, in 30 guinea-pigs, the sensitisation potential of the test element under occlusive patch.
The assay has been performed according to the OECD guideline N° 406.
The 20 treated animals were exposed 3 times to the test element by epidermal application at the concentration of 60% with olive oil.
Concurrently, the 10 control animals received olive oil by epidermal application. Following a rest period of 14 days ending the induction period, all the animals were exposed to the non irritant challenge of 60 % with olive oil.
The extent, degree and duration of skin reaction to the challenge exposure in the test animals were compared with those demonstrated by control animals.
The percentage of reactive control and treated animals was of 0%.
The test element at the concentration of 60 % in olive oil was not classified among the chemicals which may cause sensitization by skin contact.
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