Registration Dossier
Registration Dossier
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EC number: 641-088-6 | CAS number: 1229648-98-9
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- experimental study planned
- Study period:
- as soon as we receive a reply from the agency
Data source
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 315 (Bioaccumulation in Sediment-dwelling Benthic Oligochaetes)
- Principles of method if other than guideline:
- This proposal aims to justify studying bioaccumulation of Condensation Product of N-C12-C18-Alkylpropane-1,3-Diamine, N-(3-Aminopropyl)-N’-C12-C18-Alkylpropane-1,3 -Diamine and Formic Acid in a benthic species (e.g. Lumbriculus) rather than in a pelagic one (e.g. fish). For the purpose of bioaccumulation assessment, the recommended testing strategy is to perform a fish bioconcentration study for substance exhibiting Log Kow > 3.0. Such fish bioconcentration testing might be practically very difficult as Condensation Product of N-C12-C18-Alkylpropane-1,3-Diamine, N-(3-Aminopropyl)-N’-C12-C18-Alkylpropane-1,3 -Diamine and Formic Acid is slightly soluble in water and due to analytical difficulties. Considering the low solubility in water and the high adsorption potential, the substance is expected to partition to particles then to sediment. Thus, the benthic environment is expected to be the compartment of concern. Furthermore, aquatic/sediment organisms might be rather exposed via the food than by direct contact considering the adsorption properties of Condensation Product of N-C12-C18-Alkylpropane-1,3-Diamine, N-(3-Aminopropyl)-N’-C12-C18-Alkylpropane-1,3 -Diamine and Formic Acid. To conclude, a sediment bioaccumulation study is believed to be more relevant than a fish bioconcentration study for the purpose of a bioaccumulation assessment.
Test material
- Reference substance name:
- Not assignable, UVCB
- EC Number:
- 641-088-6
- Cas Number:
- 1229648-98-9
- Molecular formula:
- No molecular formula
- IUPAC Name:
- Not assignable, UVCB
Constituent 1
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
