Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Due to the nature of the end use of the substance (cosmetic ingredient) the registered substance UC was not used for animal testing. A surrogate substance Undecenyl methoxycrylene has been identified as the most suitable substance to conduct the animal studies on, therefore the classification for UC has been based on the results from Undecenyl methoxycrylene.

Migrated from Short description of key information:
Undecenyl methoxycrylene - this substance has been identified as the most appropriate 'read-across' substance.
OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
According to the Klimisch Scale - Reliability 1

Justification for classification or non-classification

From the data from the key study (Undecenyl methoxycrylene: LOCAL LYMPH NODE ASSAY IN THE MOUSE ), a Stimulation Index of 0.72 was achieved. A positive reaction is identified if the Stimulation Index equals >=3. Therefore, according to these results UC is considered to be non-sensitising.