Registration Dossier
Registration Dossier
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EC number: 700-604-0 | CAS number: 947701-81-7
Endpoint summary
Administrative data
Description of key information
The structurally similar material, undecenyl methoxycrylene (UMC), was tested in vitro in the Episkin Reconstituted Human Epidermis Model for skin irritation. The eye irritation potential of the surrogate material UMC was tested for eye irritation potential in vitro in the SkinEthic Reconstituted Corneal Model.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Skin Irritation:
The structurally similar material, UMC, was rated "not irritating" when tested in vitro in the Episkin Reconstituted Human Epidermis Test. These results suggest that there is very little potential for the test material to be an irritant and would not be classified as dangerous according to either the DSD or GHS.
Eye Irritation:
The structurally similar material, UMC, also produced a negative response for eye irritation, when tested in the SkinEthic Reconstituted Corneal Model using human corneal epithelial tissue. These results suggest that the test material has little or no potential for eye irritation.
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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