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EC number: 287-024-7 | CAS number: 85408-62-4
Not classified for acute oral, dermal or inhalation toxicity; therefore, no DNEL needs to be derived for acute/short-term exposure.
Key DNELs for workers are Long term-systemic- dermal DNEL of 28.3mg/kg/bw/day and Long term –systemic –inhalation DNEL of 58.83 mg/m3, both of which will be taken forward to the risk characterisation section of the chemical safety report. No test-item related effects were seen in any of the studies conducted relating to long-term local effects (dermal). With regard to long-term local inhalation effects, no relevant local effects were seen in either the oral or dermal repeat dose toxicity tests; therefore, it is unlikely that the test item will cause any long-term local effects via the inhalatory route of exposure. The registered substance is a mild skin irritant but no dose response data was available within the relevant studies and the substance is not classified for this endpoint and therefore no DNEL has been derived. The registered substance is classified as an eye irritant but no dose response data was available from the relevant eye irritation studies and therefore no DNEL has been derived for this endpoint and a qualitative assessment will be documented within the risk characterisation section of the chemical safety report.
Key DNELs for general population are onlyrelevant for exposure to humans via the environment as consumer end use in cosmetic products is exempted. Therefore the only relevant DNEL is Long term- systemic-oral of 5 mg/kg/bw/day for potential human exposure via drinking water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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